The relationship of ceruloplasmin and neural tube defects

J Turk Ger Gynecol Assoc 2010;11(2):86-88

DOI: 10.5152/jtgga.2010.05

1. Gaziantep University Faculty Of Medicine Obstetric And Gyneacology Department Gaziantep,Turkey

2. Department Of Obstetrics And Gynecology, Faculty Of Medicine, Gaziantep University, Gaziantep, Turkey

3. Harran University Faculty Of Medicine Department Of Biochemistry Sanliurfa,Turkey

No information available.

No information available

Received Date: 05.02.2010

Accepted Date: 24.03.2010

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ABSTRACT

Objective:

To compare the levels of ceruloplasmin (cp) in the amniotic fluids and maternal bloods of second trimester fetuses with and without neural tube defects (NTD).

Materials and Methods:

66 pregnant women were included in the study. Amniocentesis was performed in 32 women in a patient group diagnosed as NTD or anencephaly and 34 pregnants in a control group with positive Down Syndrome screening test. Maternal bloods were also taken. Cp was measured with Erel’s ceruloplasmin measurement method.

Results:

The cp levels of the amniotic fluid of patients and controls were not statistically different (p>0.05). The cp levels of the maternal bloods were not different in two groups (p>0.05).

Conclusion:

As an antioxidant, no relation was found bween cp and NTD.

Keywords: Ceruloplasmin, Antioxidant, Neural tube defect

The relationship of ceruloplasmin and neural tube defects

ABSTRACT

References