Plasma apelin levels in patients with polycystic ovary syndrome

J Turk Ger Gynecol Assoc 2012;13(1):27-31

DOI: 10.5152/jtgga.2011.74

1. Department Of Gynecology And Obstetrics, Haci Hidayet Dogruer State Hospital, Specialist Of Obstetric And Gynecology, Kirikkale, Turkey

2. Department Of Gynecology And Obstetrics, Faculty Of Medicine, Kirikkale University, Kirikkale, Turkey

3. Department Of Biochemistry, Faculty Of Medicine, Kirikkale University, Kirikkale, Turkey

4. Department Of Obstetrics And Gynecology, Sakarya University Faculty Of Medicine, Sakarya, Turkey

No information available.

No information available

Received Date: 15.08.2011

Accepted Date: 07.11.2011

PDF

Cite

Request

ABSTRACT

Objective:

The aim of the study was to evaluate plasma apelin levels in patients with polycystic ovary syndrome (PCOS) and healthy controls.

Material and Methods:

Plasma apelin levels, serum lipid levels, serum hormone levels, and homeostasis model assessment-insulin resistance (HOMA-IR) values of 32 patients with PCOS and 31 healthy women forming the control group were checked.

Results:

Plasma apelin levels of the PCOS group (0.350±0.083 ng/ml) were significantly higher than those of the control group (0.246±0.045 ng/ml) (p<0.001). No significant correlation was detected between apelin levels and biochemical or clinical data in PCOS group.

Conclusion:

Plasma apelin levels were significantly higher in PCOS patients.

Keywords: Apelin, polycystic ovary syndrome, Homeostatic Model Assessment insulin resistance (HOMA-IR), Ferriman Gallwey score (FGS), waist to hip ratio

Plasma apelin levels in patients with polycystic ovary syndrome

ABSTRACT

References