E-ISSN: 1309-0380
    Comparison of perinatal and maternal outcomes of severe preeclampsia, eclampsia, and HELLP syndrome
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    Original Investigation
    VOLUME: 12 ISSUE: 2
    P: 90-96
    June 2011

    Comparison of perinatal and maternal outcomes of severe preeclampsia, eclampsia, and HELLP syndrome

    J Turk Ger Gynecol Assoc 2011;12(2):90-96
    DOI: 10.5152/jtgga.2011.22
    Gökhan Yıldırım 1
    Kemal Güngördük 2
    Halil Aslan 3
    Ahmet Gül 4
    Mehmet Bayraktar 2
    Yavuz Ceylan 5
    1. Unit Of Maternal And Fetal, Istanbul Kanuni Sultan Su¨Leyman Research Hospital, Istanbul, Turkey
    2. Mardin Women’S And Children’S Hospital, Mardin, Turkey
    3. Bakirköy Kadin Dogum Ve Çocuk Hastaliklari Egitim Ve Arastirma Hastanesi, Istanbul, Turkey
    4. Istanbul Prenatal Center, Bakirkoy, Istanbul, Turkey
    5. Bakirköy Women And Children Hospital, Department Of Obstetrics And Gynecology, Maternal And Fetal Unit, Istanbul, Turkey
    No information available.
    No information available
    Received Date: 06.03.2011
    Accepted Date: 01.05.2011
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    ABSTRACT

    Objective:

    To compare maternal and perinatal outcomes in pregnancies complicated by severe preeclampsia, eclampsia, and HELLP (hemolysis, elevated liver enzyme levels, and low platelets) syndrome.

    Materials and Methods:

    Maternal and neonatal charts of 1,222 consecutive pregnancies complicated by severe preeclampsia, eclampsia, or HELLP syndrome at our maternal-perinatal unit were reviewed. Patients were divided into three groups: 903 (73.9%) with severe preeclampsia, 123 (10.1%) with eclampsia, and 196 (16.0%) with HELLP syndrome.

    Results:

    The overall incidence of adverse maternal outcome was 5.9%. The rates of adverse maternal outcomes for women with HELLP syndrome and eclampsia were higher than for severe preeclampsia (13.8% vs. 11.4% vs. 3.4%, respectively) (p=0.000). Birth weight was lower in patients with HELLP syndrome than in patients with eclampsia and severe preeclampsia (p=0.005). No significant difference in neonatal morbidity was found among the three groups. Perinatal mortality tended to be higher in the severe preeclampsia group than in the HELLP syndrome and eclampsia groups (p=0.231).

    Conclusion:

    Pregnancies complicated by HELLP syndrome had significantly higher maternal morbidity than those with severe preeclampsia and eclampsia. Perinatal and neonatal outcomes in pregnancies complicated by severe preeclampsia, eclampsia, and HELLP syndrome were dependent on gestational age rather than being disease dependent.

    Keywords: Severe preeclampsia, eclampsia, HELLP syndrome, perinatal and maternal outcome

    References

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