Case report: Methotrexate-induced pericardial effusion

J Turk Ger Gynecol Assoc 2013;14(1):48-49

DOI: 10.5152/jtgga.2013.11

Betül Dündar ¹

Alper Karalok ²

1. Department Of Obstetrics And Gynecology, Etlik Zu¨Beyde Hanim Women’S Health Training And Research Hospital, Ankara, Turkey

2. Division Of Gynecologic Oncology, Etlik Zübeyde Hanim Women’S Health Training And Research Hospital, Ankara, Turkey

3. Department Of Gynecologic Oncology, Etlik Zübeyde Hanim Women’S Health Teaching And Research Hospital, Ankara, Turkey

4. Department Of Gynecologic Oncology, Etlik Zu¨Beyde Hanim Women, Ankara, Turkey

5. Ankara Etlik Maternity And Women’S Health Teaching And Research Hospital, Gynecologic Oncology Division, Ankara, Turkey

6. Etlik Obstetrics And Gynecology Training And Research Hospital, Oncology Department, Ankara, Turkey

7. Gynecologic Oncology Division, Etlik Zu¨Beyde Hanim Women’S Health Research And Teaching Hospital, Ankara, Turkey

No information available.

No information available

Received Date: 07.08.2012

Accepted Date: 18.09.2012

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ABSTRACT

We report a case of pericardial effusion induced by methotrexate in a patient with low risk gestational trophoblastic neoplasia, who had been taking the first course of sequential methotrexate-folinic acid treatment. After aspiration of pericardial effusion another methotrexate- folinic acid course was given and the pericardial effusion did not relapse.

Keywords: Methotrexate, toxicity, pericardial effusion, gestational trophoblastic neoplasia, treatment

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