E-ISSN: 1309-0380
The role of brucella infection among women with spontaneous abortion in an endemic region
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Clinical Study
VOLUME: 9 ISSUE: 1
P: 20-23
March 2008

The role of brucella infection among women with spontaneous abortion in an endemic region

J Turk Ger Gynecol Assoc 2008;9(1):20-23
Mohammad Nassaji 1
Nahid Rahbar 2
Raheb Ghorbani 3
Sabahat Lavaf 1
1. Department Of Infectious Diseases, Fatemieh Hospital, Semnan University Of Medical Sciences, Semnan, Iran
2. Department Of Obstetrics & Gynecology, Amir Hospital, Semnan University Of Medical Sciences, Semnan, Iran
3. Department Of Social Medicine, Semnan University Of Medical Sciences, Semnan, Iran
No information available.
No information available
Received Date: 26.08.2007
Accepted Date: 12.11.2007
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ABSTRACT

CONCLUSION:

This study showed that the brucella seropositivity is no more common in women with spontaneous abortion than in normal pregnant.

RESULTS:

Both groups were matched based on age, number of previous pregnancies and abortion, gestational age and consumption of unpasteurized cheese. 6.2% of cases and 13.6% of control group had positive IgG titer (IgG ≥ 10). In both groups IgM was negative (IgM<10). There was no significant relationship between brucella antibody and spontaneous abortion. There was a significant relationship between raw milk consumption and spontaneous abortion (OR=6.31).

Materials & METHODS:

In this study 81 women with spontaneous abortion were considered as case and 105 women with normal pregnancy outcome as a control group. IgG and IgM antibody was measured by enzyme-linked immunosorbent assay method in both groups. IgG or IgM equal or greater than ten considered positive.

OBJECTIVE:

Brucella infection in animals is associated with high incidence of abortion but in human, there are controversies about role of brucellosis in spontaneous abortion. Brucellosis is endemic in Iran. Because many causes of abortion are undiagnosed, this study has been designed for the evaluation of a possible association between the previous maternal brucella infection and spontaneous abortion.

Keywords:
Brucellosis, spontaneous abortion, serology, pregnancy