ABSTRACT
The evidence of risk for birth defects due to artificial reproductive technology (ART) cycles is not yet clear. However, there may be a possible link between ART cycles and epigenetic abnormalities. Abdominal cysts are rarely seen pathologies after intracytoplasmic sperm injection (ICSI) cycles. A giant mesenteric cyst was diagnosed in one of the ICSI twins by ultrasonograhic examination at 14th gestational week. Infants born following ART are at increased risk of birth defects, compared to spontaneously conceived infants. When a mesenteric cyst is prenatally diagnosed, the differential diagnosis of enteric duplication cysts, ovarian cysts, urogenital tract malformations and biliary tract abnormalites should be done. Also we should keep in mind that mesenteric cysts may accommodate other pathologies.