ABSTRACT
To investigate whether pregnancy complications are increased in poor responders to ovarian stimulation in IVF treatment.
We reviewed the antenatal follow up and birth records of 26 poor responders to ovarian stimulation and 125 normoresponder patients in an IVF program.
Eighty nine (71.2%) of the normoresponders and 22 (84.6%) of the poor responders had no pregnancy complications. Gestational diabetes was present in 18 (14.4%) of the normoresponders and 3 (11.5%) of the poor responders. Seven of the normoresponders had placenta previa (5.6%). Two of the normoresponders (1.6%) had pregnancy induced hypertension. Two (1.6%) of the normoresponders had preeclampsia. One patient from each group had fetal anomaly (3.8% for poor responders vs. 0.8% for normoresponders). Cholestasis of pregnancy was present in two of the normoresponders (1.6%) and the 2 patients (7.7%) who delivered prematurely also belonged to this group.
Our results revealed that pregnancy complications were not increased in patients with a reduced ovarian reserve when compared to their age matched counterparts.
Keywords: Pregnancy complications, poor ovarian reserve, IVF, poor response