Original Investigation

Plasma apelin levels in patients with polycystic ovary syndrome


  • Kıvılcım Gören
  • Nevin Sağsöz
  • Volkan Noyan
  • Aykan Yücel
  • Osman Çağlayan
  • Mehmet Sühha Bostancı

Received Date: 15.08.2011 Accepted Date: 07.11.2011 J Turk Ger Gynecol Assoc 2012;13(1):27-31 PMID: 24627671


The aim of the study was to evaluate plasma apelin levels in patients with polycystic ovary syndrome (PCOS) and healthy controls.

Material and Methods:

Plasma apelin levels, serum lipid levels, serum hormone levels, and homeostasis model assessment-insulin resistance (HOMA-IR) values of 32 patients with PCOS and 31 healthy women forming the control group were checked.


Plasma apelin levels of the PCOS group (0.350±0.083 ng/ml) were significantly higher than those of the control group (0.246±0.045 ng/ml) (p<0.001). No significant correlation was detected between apelin levels and biochemical or clinical data in PCOS group.


Plasma apelin levels were significantly higher in PCOS patients.

Keywords: Apelin, polycystic ovary syndrome, Homeostatic Model Assessment insulin resistance (HOMA-IR), Ferriman Gallwey score (FGS), waist to hip ratio