Objective:

The aim of the study was to evaluate plasma apelin levels in patients with polycystic ovary syndrome (PCOS) and healthy controls.

Material and Methods:

Plasma apelin levels, serum lipid levels, serum hormone levels, and homeostasis model assessment-insulin resistance (HOMA-IR) values of 32 patients with PCOS and 31 healthy women forming the control group were checked.

Results:

Plasma apelin levels of the PCOS group (0.350±0.083 ng/ml) were significantly higher than those of the control group (0.246±0.045 ng/ml) (p<0.001). No significant correlation was detected between apelin levels and biochemical or clinical data in PCOS group.

Conclusion:

Plasma apelin levels were significantly higher in PCOS patients.

Keywords: Apelin, polycystic ovary syndrome, Homeostatic Model Assessment insulin resistance (HOMA-IR), Ferriman Gallwey score (FGS), waist to hip ratio