Original Investigation

Perinatal outcomes of 25 hiv-infected pregnant women: hacettepe university experience

10.4274/jtgga.galenos.2019.2019.0033

  • Ahmet Çağkan İnkaya
  • Gökçen Örgül
  • Nurhayat Halis
  • Şehnaz Alp
  • Ateş Kara
  • Özgür Özyüncü
  • Murat Yurdakök
  • Serhat Ünal
  • M. Sinan Beksaç

Received Date: 27.02.2019 Accepted Date: 22.09.2019 J Turk Ger Gynecol Assoc 0;0(0):0-0 [e-Pub] PMID: 31564083

Objectives:

To evaluate perinatal outcomes of HIV-infected pregnant women in Turkey.

Methods:

Maternal characteristics, pregnancy complications, laboratory findings (HIV virus load, CD4 cell count, CD4/CD8 ratio), neonatal features and final HIV status of the baby are retrospectively analyzed.

Results:

The sample includes 26 singleton pregnancies, from 25 HIV-infected women. The participants’ ethnicities are Turkish (n=18), East European (n=4), Asian (n=2) and African (n=2). The majority (76.9%) of the women aware of their HIV status before becoming pregnant. Four cases (15.3%) are diagnosed during pregnancy and two cases (7.8%) at the onset of labor. The results for median HIV viral load, CD4 count, and CD4/CD8 ratio at birth are 20 (0-34 587), 577 (115-977), and 0.7 (0.1-1.9), respectively. The positive HIV viral load rate is 5.5% in eighteen women taking anti-retroviral treatment. The rates of gestational diabetes mellitus, gestational hypertension, intrauterine growth restriction, and preterm delivery are 3.8%, 3.8%, 7.6%, and 8%, respectively. The mean gestational week at birth is 38 weeks and mean birthweight is 2972 ±329g. There are two HIV infected babies, with an infection rate of 8.3%. There is one needle-related accident during surgery.

Conclusion:

Timely diagnosis of HIV infection during pregnancy is important for preventing mother to child transmission (MTCT). HIV infected mother may give birth to HIV negative babies with the help of multidisciplinary team, composed of perinatology, infection diseases, and pediatrics specialists.

Keywords: HIV,Pregnancy,Antenatal Care,Turkey