A 35 year woman G2P0A1L0 at 16 weeks period of gestation, who underwent termination of pregnancy for fetus having a large lumbosacral meningomyelocele and Arnold chairi II malformation. She was a known case of tuberculoma of brain treated not on any antiepileptics, seizure free for the past two years. She developed two episodes of seizures precipitated during pregnancy termination with misoprostol. She received intravenous diazepam and phenytoin and was safely discharged home after she aborted.

Keywords: Seizure, misoprostol, termination of pregnancy