Original Investigation

Are pregnancy complications increased in poor responders?


  • Huriye Ayşe Parlakgümüş
  • Bülent Haydardedeoğlu
  • Erhan Şimşek
  • Tayfun Çok
  • Cem Yalçınkaya
  • Cantekin İskender
  • Esra Bulgan Kılıçdağ

Received Date: 13.08.2010 Accepted Date: 22.11.2010 J Turk Ger Gynecol Assoc 2011;12(1):1-3 PMID: 24591948


To investigate whether pregnancy complications are increased in poor responders to ovarian stimulation in IVF treatment.

Material and Methods:

We reviewed the antenatal follow up and birth records of 26 poor responders to ovarian stimulation and 125 normoresponder patients in an IVF program.


Eighty nine (71.2%) of the normoresponders and 22 (84.6%) of the poor responders had no pregnancy complications. Gestational diabetes was present in 18 (14.4%) of the normoresponders and 3 (11.5%) of the poor responders. Seven of the normoresponders had placenta previa (5.6%). Two of the normoresponders (1.6%) had pregnancy induced hypertension. Two (1.6%) of the normoresponders had preeclampsia. One patient from each group had fetal anomaly (3.8% for poor responders vs. 0.8% for normoresponders). Cholestasis of pregnancy was present in two of the normoresponders (1.6%) and the 2 patients (7.7%) who delivered prematurely also belonged to this group.


Our results revealed that pregnancy complications were not increased in patients with a reduced ovarian reserve when compared to their age matched counterparts.

Keywords: Pregnancy complications, poor ovarian reserve, IVF, poor response